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Implanon: What you need to know about side effects

February 08, 2026

Implanon: What you need to know about side effects

Looking to better understand the risks and side effects of Implanon? We have prepared a comprehensive article based on scientific studies that highlight the importance of understanding this contraceptive method.

Implanon is a subdermal implant that releases etonogestrel, a synthetic hormone. It offers up to 3 years of protection against pregnancy and is considered one of the most effective reversible contraceptive methods.

However, from an Integrative Health perspective, it's important to consider: if the goal is to address overall health, using synthetic hormones can have impacts beyond contraception.

The most frequent adverse effect is menstrual irregularity.

Many women report frequent, prolonged bleeding, spotting, or absence of menstruation.

These symptoms do not pose significant health risks but considerably affect quality of life and lead many patients to discontinue use. (Mansour D, 2008 – DOI: 10.1080/13625180701548040)

Headaches, acne, mastalgia, weight changes, mood swings, and even decreased libido can occur.

In some cases, dizziness or pain at the implant site may be experienced. (ACOG, 2022 – DOI: 10.1097/AOG.0000000000004967)

Despite its efficacy, the primary reason for discontinuation is precisely irregular bleeding and undesirable side effects. (Ali M, 2020 – DOI: 10.1186/s12978-020-01054-y)

Etonogestrel is a synthetic derivative of natural progesterone.

It does not behave exactly like the bioidentical hormone naturally produced by our bodies.

It can disrupt the hormonal axis, affect receptors, and alter a woman's natural balance.

Within integrative practice, we strive to avoid this type of interference whenever possible.

This content is part of Clínica Revitalize's commitment to translating science into accessible clinical practice — without losing rigor or depth.